<*n style="line-height:1.5;font-family:楷体_GB2312;font-size:16px;font-weight:bold;">大小鼠步态实时检测分析处理系统*n>
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<*n style="font-family:楷体_GB2312;font-size:16px;font-weight:bold;">Gait Analysis Lab*n><*n style="font-family:楷体_GB2312;font-size:14pt;font-weight:bold;">*n>
<*n style="font-family:楷体_GB2312;font-size:16px;font-weight:bold;"> 大小鼠步态(gait)是指大小鼠行走时所表现的姿态。BW-GAL1401大小鼠步态实时检测分析处理系统基于原有足迹分析方法(footprint analysis),运用新技术对足印分析法进行了改进,通过足印图像增强技术采用高速摄像机可以清晰地采集大小鼠行走过程的足印信息,然后利用步态分析系统自动识别分析大小鼠足迹的步行周期、支撑距离、支撑时长、摆动时长、制动时长、推进时长、步频等60余种指标,以此客观、准确和*地反映动物步态的变化情况。而且BW-GAL1401大小鼠步态实时检测分析处理系统集数据采集、监测、分析、统计处理、绘图制表、打印输出于一体,避免繁重的人工劳动,*大提高实验的自动化程度。BW-GAL1401大小鼠步态实时检测分析处理系统可广泛应用于脑缺血、阿尔茨海默病、*n><*n style="line-height:1.5;font-family:楷体_GB2312;font-size:16px;font-weight:bold;">*氏病、脑外伤、脊髓损伤、疼痛疾病、*等多种疾病动物模型步态的研究。*n>
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<*n style="font-family:楷体_GB2312;font-size:16px;">一、 *n><*n style="font-family:楷体_GB2312;font-size:16px;font-weight:bold;">系统构成*n><*n style="font-family:楷体_GB2312;font-size:14pt;font-weight:bold;">*n>
<*n style="font-family:楷体_GB2312;font-size:16px;font-weight:bold;">1. *n><*n style="font-family:楷体_GB2312;font-size:16px;font-weight:bold;">硬件构成*n><*n style="font-family:楷体_GB2312;font-size:12pt;font-weight:bold;">*n>
<*n style="font-family:楷体_GB2312;font-size:18px;">BW-GAL1401大小鼠步态实时检测分析处理系统硬件系统主要包括:1视频采集分析计算机(1台)、2老鼠步行通道、3高速摄像机、4足迹增强板、5背景增强系统等等。*n><*n style="font-family:楷体_GB2312;font-size:18px;">下图*n><*n style="font-family:楷体_GB2312;font-size:18px;">为步态分析系统*n><*n style="font-family:楷体_GB2312;font-size:18px;">实物*n><*n style="font-family:楷体_GB2312;font-size:18px;">图。*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;">*n>
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<*n style="font-family:楷体_GB2312;font-size:12pt;font-weight:bold;">2. *n><*n style="font-family:楷体_GB2312;font-size:12pt;font-weight:bold;">软件构成*n><*n style="font-family:楷体_GB2312;font-size:12pt;font-weight:bold;">*n>
<*n style="font-family:楷体_GB2312;font-size:10.5pt;">BW-GAL1401大小鼠步态实时检测分析处理系统软件由视频采集模块和分析模块两部分组成。*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;">*n>
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<*n style="font-family:楷体_GB2312;font-size:10.5pt;">如下图:*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;">其中蓝色矩形区域为图像实时显示区域。通过点击界面上方视频浏览工作栏,可以完成视频文件播放、倒放、单帧播放等功能。点击视频分析工具栏按钮,可以完成视频分析功能。界面上不同区域,用于显示相应的指标信息。*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;">*n>
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<*n style="font-family:楷体_GB2312;font-size:12pt;font-weight:bold;">3. *n><*n style="font-family:楷体_GB2312;font-size:12pt;font-weight:bold;">控制原理*n><*n style="font-family:楷体_GB2312;font-size:12pt;font-weight:bold;">*n>
<*n style="font-family:楷体_GB2312;font-size:10.5pt;">下图*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;">为步态实时采集处理硬件系统示意图。实验过程中,将老鼠从步行通道左入口(或右入口)放入步行通道,当老鼠沿通道直行到一*置,自动触发安装在框架底部的垂直向上拍摄的高速摄像机开始*n>
<*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">步态实时采集处理硬件系统示意图*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">:*n>
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<*n style="font-family:楷体_GB2312;font-size:12pt;font-weight:bold;">软件控制流程图*n><*n style="font-family:楷体_GB2312;font-size:12pt;font-weight:bold;">:*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">*n>
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<*n style="font-family:楷体_GB2312;font-size:14pt;font-weight:bold;">二、指标评价体系*n><*n style="font-family:楷体_GB2312;font-size:14pt;font-weight:bold;">*n>
<*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;"> BW-GAL1401大小鼠步态实时检测分析处理系统*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">能自动检测丰富*的评价指标,指标评价体系如下:*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">*n>
<*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">1*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">步行周期*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">、*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">2*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">支撑时长*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">、*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">3*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">摆动时长*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">、*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">4*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">支撑时相*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">、*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">5*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">单支撑时相*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">、*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">6*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">双支撑时相*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">、*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">7*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">三支撑时相*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">、*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">8*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">摆动时相*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">、*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">9*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">制动时长*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">、*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">10*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">制动指数*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">、*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">11*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">推进时长*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">、*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">12*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">推进指数*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">、*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">13*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">同源协调性*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">、*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">14*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">同侧协调性*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">、*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">15*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">对侧协调性*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">、*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">16*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">步幅*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">、*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">17*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">左侧步基*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">、*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">18*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">右侧步基*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">、*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">19*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">前肢步宽*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">、*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">20*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">后肢步宽*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">、*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">21*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">足迹面积*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">、*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">22*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">足迹平均面积*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">、*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">23*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">足迹强度*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">、*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">24*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">足迹平均强度*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">、*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">25*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">摆动速度*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">、*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">26*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">瞬时速度*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">、*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">27*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">平均速度*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">、*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">28*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">总速度*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">、*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">29*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">足角*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">、*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">30*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">平均体转角*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">、*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">31*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">体转角标准偏差*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">、*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">32*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">平均侧向移动*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">、*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">33*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;font-weight:bold;">侧向移动标准偏差*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;">*n>
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<*n style="font-family:楷体_GB2312;font-size:14pt;font-weight:bold;">三、应用*n><*n style="font-family:楷体_GB2312;font-size:14pt;font-weight:bold;">*n>
<*n style="font-family:楷体_GB2312;font-size:10.5pt;">BW-GAL1401大小鼠步态实时检测分析处理系统集数据采集、监测、分析、统计处理、绘图制表、打印输出于一体,避免繁重的人工劳动,*大提高实验的自动化程度。拥有多项精细的检测指标,功能强大又灵活。可适用于大、中专医学院校,科研单位进行有关脑缺血,阿尔茨海默病,*氏病,脑外伤,脊髓损伤,疼痛疾病,*,肌萎缩,运动损伤等多种疾病的机制*n><*n style="font-family:楷体_GB2312;font-size:10.5pt;">研究以及相关*筛选和作用机制的研究。*n>